SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b82bc181d407b025961f94f2e06c34effff3a1311641563b5a47570a54fb457' 
  AND token = 'iUvtQeFWJrnfFdCg+8q+5t4cCobI4ygmiQm/Zeom2Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}