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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353f979dc37b629166a08d7d33555a0d194e7ab4d082e0d1d069219ac3fecee5' 
  AND token = 'vrrxtznU/Tb16La1VS0vC+KDuubKcoM5cfHhDKgwgn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}