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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5267f4605ca59994f1f85e23535dd1a556888c885530dc7662b49300c6868670' 
  AND token = 'Ptf3reMwCq0SOgeGKfMf1k5jFh7RtCOjVY8k5wl/8MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}