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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f388ee51568ae20935010790d9c7bf6dd89220fe400c3062c5dd3f0e8c357515' 
  AND token = 'XIYGnesubwBooeoZUCI1PY6r0d7es/RVvamYdzgJkxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}