SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33125a0852bcafbd3243ab6b133a90c2306cdb714ebb1365a1969968a5ec2dec' 
  AND token = 'd2KiFjKcJrCBRNImgXLxSI1iPrvyKrqtRKWEhFRKk0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}