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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14d4678c6681f906e366e6d6850b4ed050e2b9fe55887caa52d1c2a83b73ba13' 
  AND token = 'f2ntgVN56LVsyOq0WUW8OWQWiqRUHOB50cDbiCw1GzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}