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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53322a294829af51992d9bcbbff7a0bc81e2d4cd2fdcdef8a88db62122c6385b' 
  AND token = 'OCGUxCuT8mc4xa0/4eJCWQNz+w2tJlQVrK7u58WQ6c8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}