SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817d3dcba8c17885aef5f1a32e020bc728d4dd607aca700c4555372920d89220' 
  AND token = '8N2uI5oPxxJe3Lpo7AJnGUj29NyVZpelQEdj2PmFWcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}