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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aadf913212e243a20cbd747904079cd570e8f4764a588f144ff1afb1ad62780' 
  AND token = 'OK5gu2oEHrAObqHh+UMNQ/wq2uUTEQy9BxWkYCZkS28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00099

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}