SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '857c1d4942a9e48f95cd70cdc8bbb0ca7060cd1147b24274ba8f1049c42a87fc' 
  AND token = 'eBPspAiVI/4i+fVB9+8UHQkIvAKn6puPV2ck6h2z4RY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}