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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa4714b72729fec2d992c86bf5399cc30e653c781fc012e880bbcdb0e37c9ce' 
  AND token = 'HeQ2Pa5DBqn02KLFp3zJ0XAvwpI55pkwSfRDIPwhMSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}