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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33bc40a4de1bddc4ba246fdcaea161644e4af0e281a6ba851691a32f2179220c' 
  AND token = 'd7LckTvzkpEVxcqfN+xcDxIs7EyiVGHrgcZEBT0WNok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}