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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbbf42bddb4f90d27ffe820ec9d353352311bd26fc5d1e9f652cb32d5e9e7019' 
  AND token = 'S5+RSPyMVCB8s3UCtZfobd5xo3aVT/AoV+NRMu1XZlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}