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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1a67c991f602f9ac85d95cd2b835f153387445248ebcd1b4a186095eecf9b1' 
  AND token = 'wi1XJjYrHI+fdtPpyy+0dasD0hXPVwo4xbHVkW2oJJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}