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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52b0cf01e5ea00bc07476231f3e548382152bf0f389544c0f5bc0199f0eeeaeb' 
  AND token = 'xqbT7tTxN9kC1vPRD6RpJ1fTY7lNQoI0d6N1NcgbzVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}