SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86606f1d65b31b04cbb6243a44f7ebab3a59794d775fb02eb5d30d3fe21b1596' 
  AND token = 'BmqdsoEg4T1JSGiVr9PuhxVyVglDV5DIRRfSsFHEiaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}