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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d53f5fdedf8ca8778840e41cc125d225c0e3f759502fb777552218a8ffaef8b' 
  AND token = 'fx7Cynrcr0sCYvaI8GfQOZLqPdkmSfYNI/4oBqbl0ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}