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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95ed16bf2b97956c2934b6dcefa96c3375c094505adbaa0ca403c64ec8346eb4' 
  AND token = 'lOMjnLgGqVLvRlrLnT0vHsTKdeM7DTc1X1yu1XO2GT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}