SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '007e871efeb890c99cb5203b2a9ea727da13b36880607b8991fe418d28f10f00' 
  AND token = 'acKzr+Mm1BuIPhlJiFORV494MG2g3lylKouBpsBd3Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}