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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4e63f61418e2d24c6e94ff1f753d677e4fad24ad5dd64a5ac33af6867da9b71' 
  AND token = 'uv6OnVAdEZgjw9tMNtHJjZwT40g3a6p5ix2EYTAqmwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}