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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1dc0aeea0120da98ea727bc9319dd67f9b7db946d66b3c30f822152bc450b5b' 
  AND token = 'F/74XAWNb5klrnMwR04wwmYUw8lTbhFcG+1Ktcn7Fjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}