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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d07b45e3071c25cd3e6b0f616f790784870528ba0e7450b22f9200390066324' 
  AND token = 'x2qgL2w0S+UllqWLBBz3X76mLKSICgedO++TkrBOMWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}