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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d0a78b5ca8302d936da25a2bd3e2abb6340a5ad01899cbe1c051dca7756301' 
  AND token = '7uYYhAoiDJ3bsE+6bEYqrTDomgApDeuDLbsRjaJsre8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}