SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b6eb6bc8550cf9930aae0800b50f595ecca3fa1a97deb3ac968bb999252f7ce' 
  AND token = 'O3gRM7mdTnSJneD02GjyP080T8qu4MArXwBAZK4ClDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}