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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f653c20d26095cb48914a177a3d6fe6abfaea9501d35b73931e720103156367' 
  AND token = '4aPW3D8TRmtHJOYmDxdpUM5/L38ejNcF+ODsNLaY69E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}