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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c59a66f993e7b0552cfa136fd04b8b79766c8b0a940e295cf397e96997780ab4' 
  AND token = 'IT66eOrDZ8vA2Mkdr/6Vebh1dui3NLHvtHijYJ1OFL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}