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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aad43e620edd6d05691f2f847231c568610203032a7649c4fcb7dc9f5670410' 
  AND token = 'J2a1v/Jbik0XbYrEWS4VgWoB+IOfDuIzUm2dsL+bzRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}