SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f9e56631da74294fa24da5b52b7da3c00e249743ce87f88c519c2a527482d1' 
  AND token = 'TWNE3eu3BFevHBlIyTW9cvtt7vE9RHS+PM2R/cI4kNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}