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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780203016dcdf2ecbd5cd37e95e95657e0ed4529f63dd656de19ec98199c61f9' 
  AND token = 'q4Wp1zeSJujF2KwnZuHScMNosLejb0bH+9secxW2kpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}