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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d0b4e84739c38ad91775b873bdac23b4516ac2520883e3216b076db2404cae9' 
  AND token = '7vN64/Kcs/iehpfU+wQ8wVd0VTyq7HtfS4NJEu4A9f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}