SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0291793424a04838e4c7bd45acccb493738ed2ba1d1fc65144281a0bb643790b' 
  AND token = 'fcqopEyJvYH1DvOn98bbCpG5hCpLBjygL9BE/GLf7Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}