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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa2edb46c93bca6cf9e877948d844f87e98249fa5c920bb4a4bd2ad338b146a4' 
  AND token = 'BwTUsmmuMNDU0Bwlqs7XZNa5KGeS2fadO8d42Ty3eBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}