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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3170de91c807a6bbac01e0309ee4e130c64d2f9f91542dc5fd442c0fec173c0' 
  AND token = 'NxzFsBMcYSE5+R3a3tCsLrGuqCV9d3EqWaIeuR1XHYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}