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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0b77ac10a58f5856f9a0faad0e629a93e9df22f8572c974166d88e7d224593' 
  AND token = 'GViRhWmtocdtWdmD4oohYoAr8aXG9lJxtujPKlb8DAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}