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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd5f8524efe9c1adf8e193732c9ea25cd21bfb4f85b4349e72b26952999b750' 
  AND token = 'yneFKoy92ZIvnW4zS1B9GtpOhnPYB3zbi0Xg8tdlofU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}