SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddb106cc55c9b620a27e94be50f0bc8edac3592b359fc562a49aa893f4906704' 
  AND token = '6GNhF0dYIqWFaXSIjCTKp+szV35m2rYdTTpYiGVRTyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}