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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b423c947dc52bb45a14c4928b6c321165b2067724085a5d6723f24d1b26380' 
  AND token = '3VW9So/VtgYQw6GsYBN3wJQJRjejB06T8M9R5cHc8IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}