SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7adb5c74a8547040022eccd2c68df6c7faf24d5d5aa6c0f00f2129bd8d4d95a5' 
  AND token = 'iCTAAtUmvIgvF/3hSnpLfT2moHpLRpamNWDmLSQAKAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}