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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c7b4cbd5247bd53fef297a47b2372dd56d90e61dd2402ff5dcd7dd3c625afd5' 
  AND token = 'aKreuTFKEp7W2giVHib6roNxiBLOk9ZxPolZaa0Q7S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}