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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '257cab5ec7c4f4d34f72c7faa217cff0f46afc6c6d6dbc0d037621483cd6c005' 
  AND token = 'lrSZV0flvtaRfrz6+sik8xCD0cLlLbUrsKXaHJKaXng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}