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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c8ff8803c746d81d9e5ce86acb214fd03959f7b42bf1d158008b0dea408b09' 
  AND token = 'p1IuInsYY9+NFMDct380pAKz3ZvdgV5LGQv/u3+etnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}