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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79db7cbb493a19b24ab25924e7180988ca0eaf0a89ca2909c7a3f4ff4e565626' 
  AND token = 'LiAET5r9PXCesHcO4inirCxbCINEBYrR/TFz53htedM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}