SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86eb455a0165ed8450e08ee7224d9ffd122e851121a4d859349cf5ee4daed3fa' 
  AND token = 'U4HwE71uLQt7bliFhVbhGJUQfXJZELK+e/1pozI/neY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}