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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b627a481e3b4a812ebc1a591a8c9ccd01339c976684c71a5283a3935c027317' 
  AND token = 'CP81/AOJHeAfEaCLkUGtYbkaCju01q8bto60T5ERNNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}