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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cf6d8e2e446025ab5cbf682e9a7c2054ac1bd19190fcbc31f34f6a4476321d3' 
  AND token = '75aIkoJCPzIkfreyfUAuC5vGGDhtWnyYmkyHQ0r55nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}