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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9835726bfdafc822da9b68c6665177635c05827b3942089efbcc10bbe19c9437' 
  AND token = 'h6mi71HsbKeM52CPCDW9WlC7a4EEgE8DI0zZgIrfjZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}