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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52b4972d48d614b42fc1c8b6b5c1e7dd505361e5e1004d0eda02d57072212c0f' 
  AND token = 'ZlP/anNKsOs9G1yLcBI8ZgBAEf97ORqS4VgRttTwY4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}