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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5dbb3791f9c886f96491bbbbc105a33d64aa2bcdcdda5561a9919a759a0c72' 
  AND token = 'jm25w9GS170Gd06gzS8x1GecCcvswEWdhd+rWv8be40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}