SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d51183c414fd668e6b9c5942ef459162f9a7753b5dced589f4ce6df9671eeb8' 
  AND token = 'RM8N7eIAtj06iQ4sHoPwLN40a7qEfgK+pdOUpDbZStA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}