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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '333a73595d68d691eb94cb3816c2e1c79dbb271d2d7e5b3ece6eedd2bb71afb1' 
  AND token = 'x5HUVjKwzjL20fUK7vdc/jMi4g5Ye3xuVJizAnXdLKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}